Studies: Crotoxin and snake venom-derived research (2016–2026)

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Therapeutic Potential of Snake Venom Toxins for CNS Tumors: A Review”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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The World Health Organization (WHO) has published a first set of Target Product Profiles (TPPs) for the treatment of snakebites using novel therapeutics. The objective of these TPPs is to provide researchers, regulators and manufacturers with essential information about the minimum and optimum characteristics of potential treatments for snakebites, whether small molecule drugs or engineered antibody biologics.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Oral Nano-Delivery of Crotoxin for Experimental Ulcerative Colitis”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Snakebite globally claims more than 100,000 lives per year and results in morbidity for 400,000 survivors. Current treatment uses antibody-based antivenoms which are constrained by their efficacy, safety and cost. In this study we evaluated the efficacy of previously described repurposed drugs against viperid snakes of the medically important Bothrops genus. Despite variable toxin representation and bioactivity across this central and south American genus, we found that the lead inhibitors targeting metalloproteinases (marimastat and DMPS) and phospholipases (varespladib), demonstrated pan-species neutralisation in enzymatic assays, whilst nafamostat (serine protease inhibitor) had variable activity. The metalloproteinase inhibitors protected against the procoagulant and haemorrhagic effects of several venoms in phenotypic assays. Collectively these findings demonstrate that repurposed…

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin B Blocks Voltage-Gated Calcium Channels (CaV1.2 & CaV2.2)”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “In silico Approaches for Venom-Inspired Peptide Design”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Neurotoxic Snake Venoms in Mexico: Diversity and Recent Advances”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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ABSTRACT Snake toxins are widely studied owing to their importance in snakebite accidents, a serious public health issue in tropical countries, and their broad therapeutic potential. Isolated fractions from venom produced by snakes of the genus Crotalus sp. present a wide variety of pharmacological uses such as antifungal, antiviral, antibacterial, and antitumor properties, among other therapeutic potentialities. Given the direct effect of this venom on tumor cells, isolation of its compounds is important for the characterization of its anticarcinogenic actions. Crotalus durissus terrificus venom and its toxins have been widely evaluated as potential candidates for the development of new antineoplastic therapies that are efficient against different tumor lines and cellular targets. This review highlights the venom toxins of this species, with a focus on their antineoplastic properties.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Animal Venom in Modern Medicine: A Review of Therapeutic Applications”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Potential of Venom-Derived Compounds for New Antimicrobial Agents”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Systematic Review of Global Patents for Snake Venom-Derived Therapeutics”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Progress and Challenges in Snakebite Envenoming Therapeutics”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom-Derived Peptides as Next-Generation Anticancer Candidates”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Targeted Nanocarriers for Combating Glioblastoma with Venom Peptides”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Melanoma, a highly aggressive skin cancer originating in melanocytes, poses a significant threat due to its metastatic potential. While progress has been made in treating melanoma with targeted therapies and immunotherapies, challenges persist. Crotoxin (CTX), the principal toxin in Crotalus durissus terrificus snake venom, exhibits various biological activities, including anti-tumoral effects across multiple cancers. However, its clinical use is limited by toxicity. Thus, exploring alternatives to mitigate adverse effects is crucial. This study investigates the antitumoral potential of CTX in its native and in a detoxified form, in melanoma cells. Firstly, we demonstrated that detoxified CTX presented reduced phospholipase activity. Both forms proved to be more cytotoxic to SK-MEL-28 and MeWo melanoma cells than non-tumoral cells. In SK-MEL-28 cells, where cytotoxic effects were more p…

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Mammary gland tumors are the most prevalent neoplasm in intact female dogs, and they are good natural models to study comparative oncology. Most canine mammary malignancies, as in women, are commonly refractory to conventional therapies and demand ...

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Mammary gland tumors are the most prevalent neoplasm in intact female dogs, and they are good natural models to study comparative oncology. Most canine mammary malignancies, as in women, are commonly refractory to conventional therapies and demand ...

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Snakebite envenoming results in ~138,000 deaths per year, with close to four times as many victims left with life-long sequelae. Current antivenom therapies have several limitations including high cost, variable cross-snake species efficacy and a requirement for intravenous administration in a clinical setting. Next generation snakebite therapies are being widely investigated with the aim to improve cost, efficacy, and safety. In recent years several small molecule drugs have shown considerable promise for snakebite indication, with oral bioavailability particularly promising for community delivery rapidly after a snakebite. However, only two such drugs have entered clinical development for snakebite. To offset the risk of attrition during clinical trials and to better explore the chemical space for small molecule venom toxin inhibitors, here we describe the first high throughput drug s…

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WHO fact sheet on snake antivenoms with key facts and providing information on global situation, challenges producing antivenoms, weak health systems and lack of data and WHO action.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Role of Neutrophils in Tissue Repair Post-Snake Venom Injection”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Anti-inflammatory Eicosanoid Induction by Crotoxin in Macrophages”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Targeted Nanocarriers for Combating Glioblastoma with Venom Peptides”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Next-Generation Antivenoms: Challenges in Clinical Translation”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Peptide and Peptidomimetic Therapeutics in Anesthesiology”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom Peptide Analogue BF9-N17K for XIa Selectivity”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Antivenom Use and New Therapeutics R&D Landscape (2015-2022)”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotamine as a Cell-Penetrating Peptide for Gene Delivery”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Plant-Derived Snake Venom Toxin Inhibitors as Potential Therapeutics”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Varespladib Phase II Clinical Trials for Snakebite Envenoming”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Snake venom activity exhibits evolutionary patterns within genera and varies according to ecological niche. By examining venoms from species inhabiting distinct environments, niche-specific functional differences can be uncovered. Bothrops, a diverse and medically important Neotropical pit viper genus, shows known clade-specific differences in coagulotoxicity. Here, we expanded this framework by assessing intra-clade variation in cellular activity across twelve Bothrops species using a high-content fluorescence assay that simultaneously measures ion channel responses and membrane cytotoxicity. Most venoms induced rapid membrane damage and cell lysis, whereas arboreal species lacked both activities, suggesting reduced selection for these activities. In contrast, the terrestrial Bothrops mattogrossensis and Bothrops pauloensis, which are sister species inhabiting the Pantanal wetlands and…

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Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions. Peptide toxins isolated from animal venoms ...

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom Variation and Treatment Failure Causes”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Repurposing of Small-Molecule Inhibitors for Snakebite Therapy”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin Mechanisms in Pancreatic Cancer Cell DNA Damage”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom Components in the Treatment of Coagulation Disorders”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Haempatch: A Factor Xa-like Protein for Procoagulant Therapy”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Neurotoxic Mechanisms of South American Rattlesnake Venom”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Selective Modulation of Osteoclast Function by Bothrops moojeni Venom”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Varespladib: A Broad-Spectrum Snake Venom PLA2 Inhibitor”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Fractal Dimension in Liver Histology of Rats Intoxicated with Crotoxin”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Integrative 'Venomics' of the Brazilian Rattlesnake”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Patient satisfaction is a useful predictor of adherence and outcomes of cardiovascular diseases (CVDs) treatment. This study explored the satisfaction of Vietnamese CVDs inpatients and outpatients using a scale specifically designed for CVDs patients and examined the factors associated with satisfaction towards CVDs treatment services. Interviews of 600 patients at the Hanoi Heart Hospital were conducted. We developed a measurement scale for both inpatient and outpatient services. Multivariate Tobit regression was used to determine the associated factors with patient satisfaction. For inpatients, Cronbach’s alpha reported for the domains were in the range of 0.72–0.97, while for outpatients, Cronbach’s alpha was within 0.61–0.97. Overall, patients were more satisfied with inpatient services (Mean = 81.8, SD = 5.8) than outpatient services (Mean = 79.7, SD = 5.2, p<0.05). In inpatients,…

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Anti-HIV Action of Snake Venom L-Amino Acid Oxidases”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Vipegitide: A Novel Antiplatelet Compound in Preclinical Research”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin and Hepatitis C Virus (HCV) Inhibition Mechanism”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin-induced Cell Cycle Arrest in S-phase (SK-MES-1 cells)”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Pro-coagulant Activities of Russell's Viper Venom: Factor V & X”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions. Peptide toxins isolated from animal venoms ...

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Anticoagulant Actions of Protein C Activators from Agkistrodon Venom”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin-induced Lipoxin A4 Release for Antineoplastic Action”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Marimastat: A Small Molecule Inhibitor for SVMP-rich Venoms”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom Metalloproteinase Inhibitors: Future of Envenomation Therapy”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin and Angiogenesis: Reduction in Mediators from Macrophages”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin and Angiogenesis: Reduction in Mediators from Macrophages”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom C-Type Lectin-like Proteins in Platelet Modulation”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “A Review and Database of Snake Venom Proteomes”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This case study entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Phase I Trial of Crotoxin (NSC-624244) in Advanced Cancer (Update)”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Mechanisms of Snake Venom Neutralization by Herbal Compounds”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Integrative Analysis of the Venom of Crotalus durissus terrificus”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin Down-modulates Functions of Bone Marrow Neutrophils”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Disintegrins as Blockers of Integrin Alpha-v Beta-3 in Metastasis”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Disintegrins and their Applications in Cancer Therapy”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Antitumor Effects of Snake Venom L-Amino Acid Oxidases”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Structural Insights into Crotoxin Heterodimeric Assembly”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Viperatide: A New Venom-Inspired Peptide for Heart Failure”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Pro-coagulant Activities of Russell's Viper Venom: Factor V & X”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Syk-GTPase Pathway Impairment by Crotoxin in Neutrophils”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This news entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom from Deadly Toxins to Life-saving Therapeutics”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin Inhibition of Esophageal Carcinoma (Eca-109 cells)”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This case study entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Cenderitide Clinical Trials for Chronic Heart Failure”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Antifungal Activity of Crotamine Against Candida parapsilosis”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions. Peptide toxins isolated from animal venoms ...

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin Potentiates Tyrosine Kinase Inhibitors in Lung Cancer”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Mechanisms of Snake Venom Neutralization by Herbal Compounds”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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Introduction Evidence for minimally symptomatic Ebola virus (EBOV) infection is limited. During the 2013–16 outbreak in West Africa, it was not considered epidemiologically relevant to published models or projections of intervention effects. In order to improve our understanding of the transmission dynamics of EBOV in humans, we investigated the occurrence of minimally symptomatic EBOV infection in quarantined contacts of reported Ebola virus disease cases in a recognized ‘hotspot.’ Methodology/Principal Findings We conducted a cross-sectional serosurvey in Sukudu, Kono District, Sierra Leone, from October 2015 to January 2016. A blood sample was collected from 187 study participants, 132 negative controls (individuals with a low likelihood of previous exposure to Ebola virus), and 30 positive controls (Ebola virus disease survivors). IgG responses to Ebola glycoprotein and nucleoprotei…

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Structural and Functional Diversity of Snake Venom Phospholipases A2”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin as an Immunomodulator in Chronic Pain Models”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This white paper entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Snake Venom-derived Drugs for Cardiovascular Diseases: A Patent Review”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This review entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Disintegrins and their Applications in Cancer Therapy”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.

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* This publication entry summarizes publicly available literature on Crotoxin, snake venom-derived therapeutics, or related mechanisms, titled: “Crotoxin Toxicity Mitigation via Nano-encapsulation”. We could not reliably retrieve an author or publisher abstract from the linked page (access limits, non-HTML content, or missing metadata). Open the source link for the full text.